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. 2019 Oct 18;9:346. doi: 10.3389/fcimb.2019.00346

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Copyright © 2019 Zhu, Liu, Li, Zhang, Zhang, Chen, Zhao, Chen, Gu, Min and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Microbial profiling analysis in IBS and healthy controls. (A) Volcano Plots showed that there were 19 significantly up-regulated (red dots) and 12 markedly down-regulated (green dots) microbial populations in IBS patients compared to the healthy controls. (B) PCA plots showed the IBS patients couldn't be discriminated from the healthy controls. (C) The heatmap profile showed that all microbes detected were divided into 10 clusters, and no single genus or genus cluster could clearly identify IBS from the healthy controls.