Table 2.

Major differentially abundant fecal metabolites (abundance%) in IBS patients and healthy control.

Metabolites	Irritable bowel syndrome (n = 15)a	Healthy controls (n = 15)a	P-valueb	Q-valuec
8.11.14.Eicosatrienoic.acid	0.4015 (0.2588 to 0.7323)	0.02651 (0.01306 to 0.03774)	<0.0001	<0.0001
Capric.acid	0.01297 (0.005925 to 0.02282)	0.001884 (0.001097 to 0.003060)	<0.0001	<0.0001
Gamma.Aminobutyric.acid	0.9264 (0.5549 to 1.3016)	0.07469 (0.03423 to 0.1132)	<0.0001	0.0005
L. Homoserine	0.4402 (0.1948 to 0.7920)	0.06821 (0.04100 to 0.1421)	<0.0001	0.0005
L. Isoleucine	0.4013 (0.1336 to 1.1719)	0.02851 (0.01412 to 0.04918)	<0.0001	0.0005
L. Leucine	0.7815 (0.4295 to 2.2872)	0.04603 (0.02629 to 0.08831)	<0.0001	0.0005
L. Methionine	1.4862 (0.9226 to 11.4553)	0.1517 (0.1288 to 0.3844)	<0.0001	0.0005
L. Norleucine	0.2561 (0.1172 to 0.5144)	0.01578 (0.007898 to 0.02883)	<0.0001	0.0005
L. Phenylalanine	0.3267 (0.2405 to 0.7910)	0.03863 (0.01623 to 0.07230)	<0.0001	0.0005
L. Tryptophan	0.04805 (0.03404 to 0.09940)	0.01058 (0.006317 to 0.02460)	<0.0001	0.0005
L. Valine	0.5246 (0.2964 to 1.2419)	0.04274 (0.01852 to 0.06188)	<0.0001	0.0005
N. acetyltryptophan	0.06159 (0.05240 to 0.1753)	0.01155 (0.007426 to 0.02833)	<0.0001	0.0005
Oxoadipic.acid	1.7699 (0.8611 to 3.1822)	0.1248 (0.06129 to 0.3714)	<0.0001	0.0005
Putrescine	0.3064 (0.1681 to 0.5475)	0.01038 (0.004429 to 0.05220)	<0.0001	0.0005
Ornithine	0.2858 (0.1309 to 0.6154)	0.02619 (0.01670 to 0.03983)	0.0001	0.0005
Homocysteine	15.5655 (10.8261 to 29.2755)	3.4294 (0.7598 to 22.3389)	0.0186	0.0569

^aConcentrations are presented as median (interquartile range).

^bObtained from Mann-Whitney U test.

^cFDR adjusted p-value.