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. 2019 Oct 18;10:2464. doi: 10.3389/fimmu.2019.02464

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Copyright © 2019 Arias, Goig, Cardona, Torres-Puente, Díaz, Rosales, Garcia, Tapia, Comas, Vilaplana and Cardona.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Taxonomic composition of the intestinal microbiota based on 16S rRNA sequencing at week 28 after starting both diets. Analysis of the relative abundance of the most abundant phylum (A), class (B), order (C), family (D), and genus (E) in ND vs. HFD. (F) Bar plot representation of the OTUs of each sample according the taxonomic classification. (G) Regression plot of Firmicutes and Bacteroidetes phyla against animal weight and analysis of the F/B ratio in ND and HFD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; Mann–Whitney test.