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Mice exhibited depression-like phenotypes within 3 weeks of WIRS. (A) Immobility time in the FST. (B) Sucrose preference in the SPT. (C,D) Actual (C) and relative (D) body weight change. Control group:N = 4, stressed group: N = 8. (A,B) ∗p < 0.05, Mann–Whitney U-test; (C,D) ∗∗p < 0.01, Unpaired t-test. (A,B) Boxplots show 25% quartile, median, and 75% quartile of distributions; (C,D) Data are presented as means ± SEM.
