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. 2019 Oct 24;9:15258. doi: 10.1038/s41598-019-51746-0

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Functional groups over-represented among potential M2-1 binding partners. A gene set enrichment analysis was performed using BiNGO software on all potential M2-1 binding partners. P-values were determined by a hypergeometric test (alpha = 0.01) with a Benjamini & Hochberg correction. All GO terms related to biological processes found among this selection are displayed as circles, organized from the most general at the bottom to the most specific at the top. GO terms in an inclusion relation are linked by an arrow, with the arrow’s head pointing to the daughter GO term. Each circle’ diameter varies according to the GO term’s total size, and its color varies according to its enrichment p-value. GO terms which aren’t significantly enriched in the analysis are shown as blank circles. Abbreviations used: macromolecule = macMol, metabolic process = MetPro, development = dev, biosynthetic process = BiosyntPro. Response = resp (a). Complete graph. (b) Area with GO terms related to RNA metabolism.