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. 2019 Oct 15;11:29. doi: 10.3389/fnsyn.2019.00029

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Copyright © 2019 Barros-Zulaica, Rahmon, Chindemi, Perin, Markram, Muller and Ramaswamy.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fitting in vitro data to the TM-model. (A) Example of an in vitro mean voltage trace of L5_TTPC connection. (B) Corresponding deconvolved voltage trace (red) with the fit to the deterministic TM-model (gray). (C) Distribution of the probability of release parameter (U), (D) distribution of the time to recovery from depression (D) and (E) distribution of the time to recovery from facilitation (F). Values obtained from the fitting to the TM-model of 33 in vitro connections.