Table 1.
Characteristics of patients with and without septic cardiomyopathy
| Septic cardiomyopathy (n = 18) | No septic cardiomyopathy (n = 6) | |
|---|---|---|
| Age (years); median (IQR) | 62.0 (43.8–67.0) | 57 (54.0–64.5) |
| Admission APACHE II (points); median (IQR) | 18.5 (14.5–36.0) | 22.5 (20.5–23.0) |
| Female, n (%) | 7 (39%) | 5 (83%) |
| Septic shock, n (%) | 8 (44%) | 3 (50%) |
| Elixhauser comorbidity score (points); median (IQR) | 17 (6.8–26.0) | 9.5 (4.3–11.8) |
| Mechanically ventilated, n (%) | 7 (39%) | 1 (17%) |
| Duration of mechanical ventilation among those ventilated (days); median (IQR) | 1.7 (0.8–2.4) | 2.8a |
| ICU length of stay; median (IQR) | 3.7 (2.5–4.7) | 2.9 (2.5–3.3) |
| Hospital length of stay; median (IQR) | 8.0 (5.0–13.6) | 5.6 (5.1–6.0) |
| 90-day mortality | 4 (22%) | 0 (0%) |
|
Echocardiogram data Median (IQR) | ||
| LV GLS | − 11.4 (− 13.6 to − 8.4) | −19.8 (− 21.0 to − 17.3) |
| LV ejection fraction % | 57 (45–66) | 66 (64–68) |
| Source of infection, n (%) | ||
| Pneumonia | 7 (39%) | 1 (17%) |
| Urinary tract infection | 3 (17%) | 1 (17%) |
| Skin and soft tissue | 4 (22%) | 1 (17%) |
| Intra-abdominal | 2 (11%) | 1 (17%) |
| CLABSI | 1 (6%) | 0 (0%) |
| Unknown | 1 (6%) | 2 (33%) |
| Bacteremia present | 7 (39%) | 2 (33%) |
| Organism type, n (%) | ||
| Bacterial | 13 (72%) | 3 (50%) |
| Viral | 1 (6%) | 0 |
| Mixedb | 1 (6%) | 0 |
| Unknown | 3 (17%) | 3 (50%) |
| Microbiologyc, n (%) | ||
| Gram positive | 10 (55%) | 3 (50%) |
| Gram negative | 6 (33%) | 2 (33%) |
LV left venticular, CLABSI central line-associated bloodstream infection
aOnly one patient mechanically ventilated and duration was 2.8 days
bBacterial and viral infection
cSome subjects had polymicrobial infection (gram positive and gram negative)