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CGD and control macrophage derived cytokines/chemokines upon re-priming (72 h) of M1 primed (24 h) macrophages. Macrophages of CGD patients and of controls were left unstimulated (24 + 72 h) (M0M0), or were primed (24 h), followed by withdrawal of stimulus (M1M0), or by re-priming for 72 h (M1M1; M2aM2a; M2cM2c; M1M2a; M1M2c). Released cytokines/chemokines of (A) IL-18, (B) MDC and (C) GM-CSF were quantified after 24 +72 h. N = 3, empty = control, striped = CGD.
