Table. Summary of Subject Characteristicsa.
| Characteristic | Controls (n = 48) | Individuals With Schizophrenia (n = 48) |
|---|---|---|
| Age, mean (SD) [range], y | 48.6 (13.5) [17-82] | 48.1 (13.6) [17-83] |
| Sex, No. (%) | ||
| Male | 35 (73) | 35 (73) |
| Female | 13 (27) | 13 (27) |
| Handedness, No. (%) | ||
| Right | 30 (63) | 42 (88) |
| Left | 8 (17) | 4 (8) |
| Ambidextrous | 1 (2) | 0 |
| Unknown | 9 (19) | 2 (4) |
| PMI, mean (SD) | 17.7 (5.7) | 17.9 (7.1) |
| Brain tissue pH, mean (SD) | 6.70 (0.27) | 6.55 (0.31) |
| Storage time, mean (SD), mo | 155.4 (50.0) | 148.7 (54.0) |
| Suicide, No. (%) | 0 | 12 (25) |
| Schizoaffective disorder, No. (%) | NA | 14 (29) |
| ATOD use, No. (%) | ||
| Alcohol or substance abuse | 18 (38) | 29 (60) |
| Antipsychotic | 0 | 42 (88) |
Abbreviations: ATOD, alcohol, tobacco, or other drugs; NA, not applicable; PMI, postmortem interval.
a
There were no diagnostic group differences in age, sex, PMI, storage time, or the distribution of handedness between the diagnostic groups. There was a small but significant decrease in brain tissue pH in individuals with schizophrenia (P = .01).