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. 2019 Oct 18;10:1220. doi: 10.3389/fphar.2019.01220

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Copyright © 2019 Li, Yu, Jie, Zhou, Ye, Ma, Wan, Li, Shi and Yin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative LC-MS/MS chromatographs of bilirubin and its metabolites (counts vs. acquisition time). The various ions detected are indicted in the order of their elution time. (A) Total ion current; (B) Reaction monitoring transitions of M/Z 301; (C) Reaction monitoring transitions of M/Z 315; (D) Reaction monitoring transitions of M/Z 333; (E) Multiple-reaction monitoring of M/Z 385→96.1 (donepezil, internal standard); (F) multiple-reaction monitoring of biliverdin M/Z 583→297; (G) multiple-reaction monitoring of bilirubin M/Z 585→299.