Table. Characteristics at HIV Diagnosis and Cardiovascular Disease Risk Factorsa.
| Characteristic | All (N = 61) | Normal lnRHI at HIV Diagnosis (n = 47) | Abnormal lnRHI at HIV Diagnosis (n = 14) | P Valueb |
|---|---|---|---|---|
| Age, mean (SD), y | 28.1 (6.7) | 27.3 (5.6) | 30.9 (9.4) | .19 |
| Male, No. (%) | 58 (95) | 44 (94) | 14 (100) | NA |
| Race, No. (%) | ||||
| African American | 35 (57) | 30 (64) | 5 (36) | .12 |
| White | 20 (33) | 13 (28) | 7 (50) | |
| Other | 6 (10) | 4 (9) | 2 (14) | |
| BMI, mean (SD) | 26.2 (4.0) | 26.0 (4.3) | 26.9 (2.6) | .32 |
| Hypertension, No. (%) | 4 (7) | 3 (6) | 1 (7) | >.99 |
| Tobacco use, No. (%) | 12 (20) | 9 (19) | 3 (21) | >.99 |
| Diabetes | 0 | 0 | 0 | NA |
| LDL cholesterol level, median (IQR), mg/dL | 97 (80-126) | 91 (78-125) | 107 (86-138) | .39 |
| Total cholesterol level, median (IQR), mg/dL | 163 (146-195) | 163 (146-195) | 167 (149-199) | .82 |
| Time from last negative HIV test to first HIV positive test, median (IQR), mo | 18.9 (8.1-24.4) | 16.8 (8.0-24.3) | 22.8 (17.1-24.6) | .40 |
| Time from estimated date of seroconversion to baseline lnRHI, median (IQR), mo | 10.6 (5.1-13.2) | 10.1 (5.0-13.1) | 12.1 (9.4-13.4) | .35 |
| CD4 lymphocyte count, median (IQR), No./μL | 552 (449-674) | 530 (436-673) | 574 (483-670) | .98 |
| HIV viral load, mean (SD) log10 copies/mL | 4.4 (0.8) | 4.4 (0.8) | 4.6 (0.5) | .20 |
| Baseline lnRHI, mean (SD)c | 0.70 (0.29) | 0.82 (0.20) | 0.30 (0.18) | <.001 |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); IQR, interquartile range; LDL, low-density lipoprotein; lnRHI, natural log–transformed reactive hyperemia index; NA, not applicable.
SI conversion factors: To convert CD4 lymphocyte count to ×109 per liter, multiply by 0.001; LDL and total cholesterol to millimoles per liter, multiply by 0.0259.
Percentages have been rounded and may not total 100.
Calculated using unpaired t test, paired t test, and Mann-Whitney test.
Calculated as the ratio of the mean pulse-wave amplitude during the 1-minute period starting 60 seconds after blood pressure cuff deflation divided by the mean pulse-wave amplitude of a 210-second preocclusion baseline period.