FIGURE 7.
Tetrahymena Mob1 accumulates in distinct populations of basal bodies. (A) Immunofluorescence microscopy of a T. thermophila exponentially growing cell expressing Mob-GFP that concentrates in posterior region basal bodies. (B) Hypothetical model. Distinct basal bodies and corresponding assembled cilia enriched in Mob1/Hippo pathway components may differentially allow the concentration of intrinsic and/or extrinsic signals. This will create territories with different biochemical features that locally regulate specific effectors.