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. 2019 Oct 18;10:2410. doi: 10.3389/fimmu.2019.02410

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Copyright © 2019 Roelands, Garand, Hinchcliff, Ma, Shah, Toufiq, Alfaki, Hendrickx, Boughorbel, Rinchai, Jazaeri, Bedognetti and Chaussabel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Abundance of ACSL1 and ACSL4 transcripts is significantly increased in the context of sepsis in five out of seven datasets. Fold changes in abundance of ACSL1 and ACSL4 is shown in sepsis vs. control groups across multiple datasets (7, 11–16). Each spot represents a single dataset, except for GSE49756/7 which shows averaged values for the GSE49756 and GSE49757 series and that also comprises GSE49755 (Figure 1). The position of the spot on the vertical axis indicates the corresponding fold change in abundance of ACSL1 (left) and ACSL4 (right). Spots are connected to dataset attributes (metadata). On the top panel attributes relevant to the group comparisons that were performed are shown (indicating which groups are being compared and whether increase in ACSLs abundance are statistically significant). On the middle and bottom panels additional attributes that describe the study populations and assays are shown.