Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Oct 18;10:2458. doi: 10.3389/fimmu.2019.02458

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Sanz, Wei, Jenks, Cashman, Tipton, Woodruff, Hom and Lee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Human B cell ontogeny. Illustration of the current understanding of B cell ontogeny in human B cells from late bone marrow (pro- and pre-B cells) through peripheral activation pathways, and into antibody secreting cells (ASC)/long-lived plasma cells compartments (PC). (→) Denotes clear literature supported associations, whereas (- - - >) represent associations which are theoretical but have literature supported plausibility. T1, transitional type 1 B cells; T2, transitional type 2 B cells; T3, transitional type 3 B cells; MZP, marginal zone precursor B cells; DN1, double-negative (IgD– CD27–)−1 B cells; DN2, double-negative (IgD– CD27–)−2 B cells; GC, germinal center; FDC, follicular dendritic cell.