Table 1.
AAs Only |
EAs Only |
All Participants |
||
---|---|---|---|---|
Characteristics | Measures | (N = 3495) | (N = 2312) | (N = 5807) |
Demographic | Age, mean (SD), ya | 71.1 (5.8) | 74.5 (7.4) | 72.5 (6.7) |
Education, mean (SD), ya | 11.8 (3.3) | 14.1 (3.2) | 12.8 (3.5) | |
Female sex, No. (%) | 2235 (64) | 1423 (62) | 3658 (63) | |
Cognitive test results, mean (SD)b | Global cognition | 0.217 (0.716) | 0.561 (0.667) | 0.354 (0.717) |
Memory score | 0.253 (0.854) | 0.532 (0.794) | 0.352 (0.839) | |
Perceptual speed | 0.192 (0.874) | 0.846 (0.831) | 0.452 (0.915) | |
MMSE | 0.205 (0.704) | 0.445 (0.582) | 0.301 (0.668) | |
APOE genotypes, No. (%) | ε2/ε2 | 34 (<1) | 14 (<1) | 48 (<1) |
ε2/ε3 | 500 (14) | 282 (12) | 782 (14) | |
ε2/ε4 | 154 (4) | 49 (2) | 203 (4) | |
ε3/ε3 | 1642 (47) | 1412 (61) | 3054 (53) | |
ε3/ε4 | 1017 (29) | 517 (22) | 1534 (26) | |
ε4/ε4 | 148 (4) | 38 (2) | 186 (3) |
Abbreviations: AA, African American; APOE, apolipoprotein E; EA, European American; MMSE, Mini-Mental State Examination.
Age and education were significantly different between AAs and EAs (P < .001).
The global cognitive function, memory score, perceptual speed, and MMSE were also significantly different between AAs and EAs (P < .0001).