Skip to main content
. Author manuscript; available in PMC: 2020 Sep 26.
Published in final edited form as: Inhal Toxicol. 2019 Sep 26;31(7):285–297. doi: 10.1080/08958378.2019.1669743

Figure 3. Sex-differences in immune cell populations in LLF 7-days post-exposure to a single dose of cSiO2 or MWCNTs.

Figure 3.

Male and female C57BL/6 mice were exposed to a single dose of cSiO2 (1 mg), MWCNTs (50μg), or dispersion media (DM) vehicle control (50 μl), and euthanized 7-days post-exposure. Whole lung lavage fluid (LLF) was collected for total cell counts (A), extracellular protein assessment (B), cytometric analysis of immune cell populations within the airspace (C, D), and eosinophil peroxidase (EPX) measurement (E). The frequency of specific immune populations expressed as a percentage of all non- and immune-related cell types; data represented as mean ± SEM, n = 4–15. * p < .05, ** p < .01, *** p < .001, **** p < .0001 compared to same-sex DM control, # compared to males of the same treatment. IM/Mo, interstitial macrophage/monocytes; MFI, median fluorescence intensity.