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. Author manuscript; available in PMC: 2019 Oct 25.
Published in final edited form as: Crit Rev Biochem Mol Biol. 2017 Feb 22;52(3):254–273. doi: 10.1080/10409238.2017.1290043

Figure 2: Metabolic potential in apicomplexan clades –

Figure 2:

The venn diagram represents the distribution of enzymes common to all apicomplexans, shared between various clades, and unique to each clade. The distribution of conserved pathways and pathways with clade-specific enzymes (≥2 in a clade) is represented as a network. The network represents KEGG pathways (nodes) connected by number of shared metabolites, with pathways belonging to a superclass (same border colours) grouped together wherever possible. Each node is represented as a circos chart depicting the number of unique enzymes present in each major clade. Conserved pathways are indicated as empty circles. The core of the network, enclosed in a dashed circle, mainly encompasses pathways from amino acid, carbohydrate, energy, and nucleotide metabolism, with quite a few conserved pathways, as well as several clade-specific pathways, especially from coccidia. The abbreviated pathway names are expanded for those in the core, and the pathways with unique enzymes, in the periphery.