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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Adv Healthc Mater. 2019 Sep 18;8(20):e1900751. doi: 10.1002/adhm.201900751

Figure 7. Comparison of LT-HSC and HSC quiescence after 7 days in conditions that led to the greatest maintenance of an HSC population when cultured in the absence (Low 1:0 HSPC:MSC) vs. presence (High 1:1 HSPC:MSC) of MSCs (gels=30, n=10).

Figure 7.

A) Fraction of quiescent LT-HSC or HSC, shown as a percentage of the initial 2000 HSPCs seeded per hydrogel condition. B) Absolute number of quiescent (G0) LT-HSC and HSCs within each sample. C) Percentage of quiescent cells calculated vs. the total number of hematopoietic lineage positive cells after 7 days in culture as a percentage of the overall hematopoietic lineage positive cell population. *: significantly different (p < 0.05) versus the quiescence in high diffusivity hydrogel containing HSCs only (Low 1:0).