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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Appl Immunohistochem Mol Morphol. 2020 May-Jun;28(5):360–368. doi: 10.1097/PAI.0000000000000761

Table 1.

Clinicopathologic parameters of gastric cancer subgroups.

Parameters total Subtype P-value
EBV MSI EMT p53-ab p53-wt
Sex 0.0002
 female 112 2 13 25 36 36
 male 309 30 21 49 147 62
Age* 57.5±0.6 56.8±2.0 67.8±2.1 56.2±1.4 59.5±0.9 52.8±1.3 <0.0001
WHO <0.0001
 well diff 32 2 4 0 21 5
 mod diff 147 4 16 8 91 28
 poorly diff 147 27 13 27 53 29
 signet ring cell 73 0 0 28 11 34
 others 22 1 1 11 7 2
Lauren <0.0001
 intestinal 176 9 18 52 107 31
 diffuse 170 14 9 11 42 53
 mixed 72 9 7 10 32 14
 undetermined 3 0 0 0 2 0
EBV <0.0001
 negative 381 0 34 72 179 96
 positive 32 32 0 0 0 0
MSI <0.0001
 stable 387 32 0 74 183 98
 unstable 34 0 34 0 0 0
E-cadherin <0.0001
 aberrant 82 3 5 74 0 0
 normal 331 24 26 0 183 98
p53 status
 mutant 229 4 14 28 180 0 <0.0001
 wildtype 179 23 17 41 0 98
T stage** 0.0037
 T1 112 12 5 11 47 37
 T2 64 3 11 9 25 16
 T3 151 10 15 34 65 27
 T4 94 7 3 20 46 18
N stage** 0.2168
 N0 176 18 15 25 69 49
 N1 58 4 6 7 27 14
 N2 58 5 5 12 24 12
 N3 129 5 8 30 63 23
TNM stage** 0.0110
 I 141 13 9 16 57 46
 II 94 9 12 17 38 18
 III 133 5 12 31 60 25
 IV 53 5 1 10 28 9

p53-wt: p53 wildtype; p53-ab: p53 aberrant

*

Age is presented as mean ± SEM (standard error of mean)

**

Based on AJCC seventh edition.