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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Ann Biomed Eng. 2019 Apr 24;48(3):940–952. doi: 10.1007/s10439-019-02269-2

Figure 3. LD50 charts of chemotherapeutic treatments on A) Caco-2 and B) SW480 cell lines.

Figure 3.

The effects of fluoropyrimidine based drugs i) 5FU, ii) F10, iii) CF10, platinum-based drugs iv) cisplatin, v) oxaliplatin, vi) topoisomerase I inhibitor irinotecan, small molecule inhibitors vii) sorafenib, viii) regorafenib, and ix) dabrafenib/trametinib combination treatment, on the proliferation and viability of the cell line in 2D and 3D organoid. Statistical significance: * is equivalent to p-value under 0.05 between 2D and 3D at the same dose.