Table 4.
Comparison of patients' characteristics and their migraine with aura (MwA) features between three groups categorized by MACS.
| Type of symptoms |
MwA-S n = 14 |
MwA-MC n = 9 |
MwA-C n = 9 |
Statistics |
|---|---|---|---|---|
| Female, n (%) | 9 (64.3) | 8 (88.9) | 8 (88.9) | P = 0.248 |
| Age, mean ± SD (range), in years | 36.71 ± 7.7 | 42.56 ± 9.2 | 34.22 ± 10.1 | P = 0.142 |
| Age at onset of migraine with aura, mean ± SD (range) | 22.07 ± 7.0 | 20.67 ± 8.1 | 16.22 ± 9.9 | P = 0.256 |
| Frequency of migraine with aura, mean ± SD (range) | 9.21 ± 5.7 | 12.44 ± 7.0 | 8.11 ± 2.6 | P = 0.226 |
| Duration of the aura, mean ± SD (range), in minutes | 30.00 ± 11.8 | 59.44 ± 44.9 | 61.11 ± 49.1 | P = 0.076 |
| Duration of the headache, mean ± SD (range), in hours | 10.57 ± 11.4 | 7.78 ± 15.2 | 5.89 ± 7.6 | P = 0.639 |
| Pain intensity (scale 1–10), mean ± SD | 6.21 ± 1.6 | 6.44 ± 2.1 | 7.89 ± 2.0 | P = 0.117 |
| Co-occurrence of migraine without aura | 3 (21.4) | 4 (44.4) | 4 (44.4) | P = 0.397 |
| Familiar history of migraine with auraa | 6 (42.9) | 3 (33.3) | 4 (44.4) | P = 0.872 |
| Scotomab, n (%) | 14 (100) | 9 (100) | 8 (88.9) | P = 0.267 |
| Zig-zag linesb, n (%) | 11 (78.6) | 7 (77.8) | 3 (33.3) | P = 0.055 |
| Tunnel visionb | 1 (7.1) | 3 (33.3) | 3 (33.3) | P = 0.206 |
| Somatosensory aura affecting handb, n (%) | 4 (28.6) | 9 (100) | 9 (100) | P < 0.001 (MwA-S vs. MwA-MC, p < 0.001; MwA-S vs. MwA-C, p < 0.001) |
| Somatosensory aura affecting headb, n (%) | 2 (14.3) | 7 (77.8) | 9 (100) | P < 0.001 (MwA-S vs. MwA-MC, p = 0.002; MwA-S vs. MwA-C, p < 0.001; MwA-MC vs. MwA-C, p = 0.031) |
| Somatosensory aura affecting legb, n (%) | 1 (7.1) | 3 (33.3) | 2 (22.2) | P = 0.277 |
| Visual higher cortical dysfunctionsb, n (%) | 0 (0) | 0 (0) | 3 (33.3) | P = 0.015 (MwA-S vs. MwA-C, p < 0.001; MwA-MC vs. MwA-C, p < 0.001) |
| Somatosensory higher cortical dysfunctionsb, n (%) |
0 (0) | 4 (44.4) | 6 (66.7) | P = 0.002 (MwA-S vs. MwA-C, p = 0.007) |
| Dysphasic higher cortical dysfunctionsb, n (%) | 1 (7.1) | 6 (66.7) | 9 (100) | P < 0.001 (MwA-S vs. MwA-MC, p < 0.001; MwA-S vs. MwA-C, p < 0.001; MwA-MC vs. MwA-C, p < 0.001) |
| MACS (≥4.5 points), n (%) | 0 (0) | 6 (66.7) | 9 (100) | P < 0.001 (MwA-S vs. MwA-MC, p < 0.001; MwA-S vs. MwA-C, p < 0.001; MwA-MC vs. MwA-C, p < 0.001) |
MACS, Migraine Aura Complexity Score; MwA-S, patients who have simple auras; MwA-MC, patients who have moderately complex auras; MwA-C, patients who have complex auras.
a
First and second-degree relatives have been considered.
b
The described characteristic occurred in the patient at least in one of MwA attacks.