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. 2019 Oct 25;19:381. doi: 10.1186/s12887-019-1758-2

Table 2.

Proportion of subjects affected by abnormal results in one or more of the three primary tests performed, overall and by age group

Entire Cohort
Mean value
(N = 265)
Ages 1–4 years
Mean value
N = 113 (%)
Ages 5–12 years
Mean value
N = 152 (%)
Any of the 3 tests performed 57 (21.5%) 22 (23.7%) 43 (31.2%)
 Mean age for any abnormality (SD) 6.17 (3.3) 2.45 (0.74) 8.07 (2.32)
Prior stroke (N = 265) 15 (5.7%) 3 (3%) 12 (8.5%)
 Mean age for prior stroke (SD) 6.4 (2.56) 2.33 (0.58) 7.42 (1.62)
Elevated TCD (N = 251) 43 (17.1%) 17 (18.9%) 18 (13.6%)
 Abnormal TCD (N = 5) 5 (2.0%) 1 (1%) 3 (2%)
 Conditional TCD (N = 38) 38 (15.1%) 20 (20%) 18 (12.3%)
 Mean age for elevated TCD (SD) 4.92 (3.18) 2.38 (0.74) 7.48 (2.56)
Neurocognitive Dysfunction (N = 246) 27 (11.0%) 5 (5%) 22 (15.5%)
 Mean age for neurocognitive dysfunction (SD) 8.04 (3.12) 2.60 (0.89) 9.27 (1.80)

One in five participants (57 of 265, 21.5%) had at least one abnormal result in the three tests performed. The most frequent findings were elevated TCD velocity and neurocognitive dysfunction