Table 4.
Evaluation of risks for colorectal cancer
| Variable | Unadjusted | P value | Adjusted | P value |
|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | |||
| BMI (kg/m2) | 1.499 (0.710, 3.166) | 0.289 | --- | --- |
| WHR | 2.138 (1.002, 4.584) | 0.037 | 2.084 (0.949, 4.578) | 0.047 |
| SBP (mmHg) | 1.286 (0.815, 1.641) | 0.055 | 1.258 (0.565, 2.802) | 0.575 |
| DBP (mmHg) | 1.372 (0.993, 1.707) | 0.051 | 1.034 (0.856, 1.413) | 0.064 |
| TCH (mmol/L) | 0.522 (0.209, 1.307) | 0.165 | --- | --- |
| TG (mmol/L) | 0.927 (0.508, 1.692) | 0.805 | --- | --- |
| LDL-C (mmol/L) | 4.301 (3.271, 5.432) | < 0.001 | 4.197 (3.144, 5.393) | < 0.001 |
| HDL-C (mmol/L) | 0.078 (0.028, 0.218) | < 0.001 | 0.124 (0.057, 0.274) | < 0.001 |
| FPG (mmol/L) | 0.979 (0.274, 3.493) | 0.974 | --- | --- |
| FABP4 (pg/ml) | 2.141 (1.352, 3.074) | < 0.001 | 1.916 (1.340, 2.492) | < 0.001 |
| FABP6 (pg/ml) | 2.767 (1.517, 3.826) | < 0.001 | 2.162 (1.046,1.078) | < 0.001 |
| CEA (ng/ml) | 1.940 (1.038, 3.479) | 0.026 | 1.713 (1.026, 3.236) | 0.040 |
| CA19-9 (U/ml) | 3.516 (0.938, 6.186) | 0.062 | --- | --- |
| Family history of CRC | 7.298 (5.210, 9.747) | < 0.001 | 5.119(3.940, 7.569) | < 0.001 |
Adjusted for WHR, SBP, DBP, LDL-C, HDL-C, CEA, family history of CRC; OR odd ratio, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, WHR waist:hip ratio, TCH total cholesterol, TG triglyceride, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, FPG fasting plasma glucose, FABP4 fatty acid-binding proteins 4, FABP6 fatty acid-binding proteins 6, CEA carcinoembryoni, CA19-9 carbohydrate antigen 19-9