(Top Left) Refractive index tomogram (A, B) and tomogram slices (C-H)
from Choi et al. [3] showing a HeLa cell.
The nucleus is visibly less dense than the cytoplasm. Brightfield images are
shown in (I, J). (Top Right) Optical diffraction tomogram slices of HT29 cells
from Sung et al. [17] with corresponding
brightfield images on the top row. The middle and bottom rows represent
different image reconstruction algorithms. In each case, the nucleus is visibly
less dense than the perinuclear region. (Bottom) Tomographic slice (D) and
3D-rendering (E) of the refractive index distribution of an NIH-3 T3 cell from
Kim et al. [13]. 3D renderings of HeLa
cell RI distributions (A, B) are also displayed. In each case, the perinuclear
region is more optically dense than the nucleoplasm. Subfigure lettering is
referenced to the original work. Reproduced with permission refs. [3, 13, 17]. 2007, Springer Nature
and 2017, 2009, The Optical Society