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. Author manuscript; available in PMC: 2020 Nov 15.
Published in final edited form as: Anal Chim Acta. 2019 Jul 9;1082:98–105. doi: 10.1016/j.aca.2019.07.015

Figure 4.

Figure 4.

A) Photograph showing a viable tissue-mimicking agarose bead soaked with McCoy’s 5A media with 10% FBS and L-glutamine. Tissues sampling occurred via 60 minutes treated thread suspended on a needle. B) Concentration dependence of diazepam in agarose beads. The ratio of diagnostic ions for diazepam and its isotopically-labelled species were plotted. Error bars represent three replicates. C) Stability profile of agarose beads infused with 250 ng/mL diazepam over a four-week period. Error bars represent five replicates. D) Representative tandem MS spectrum of 100 ng/mL diazepam doped agarose bead sample.