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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Osteoarthritis Cartilage. 2019 Jun 29;27(10):1526–1536. doi: 10.1016/j.joca.2019.06.005

Figure 1.

Figure 1.

Experimental design. 10wk C57B1/6 male mice underwent DMM surgery on their right limbs. Five days later (+0-weeks), DMM-operated limbs were either subjected to no loading (DMM-only), l.0N-loading (DMM+1.0N), 2.0N-loading (DMM+2.0N), or 4.5N-loading (DMM+4.5N) for 2 or 6 weeks. Contralateral limbs served as controls at each time point. n=7–8 mice per group. Arrows connecting panels demonstrate the experimental design and are used in all figures with multiple timepoints.