Table 2. Factors associated with valvular surgery.

	Surgery during initial stay adjusted Odds Ratio (95%CI), Multivariate logistic regression	Surgery during the global follow-up Adjusted Hazard ratio(95%CI),Cox model
Female	0.77 (0.61–0.97)	0.67 (0.58–0.79)
Age < 70 years	3.03 (2.43–3.77)	3.04 (2.63–3.51)
Predisposing diseases
Cancer	0.51 (0.36–0.73)	0.52 (0.42–0.65)
Diabetes	NS	0.73 (0.61–0.87)
Chronic respiratory disease	NS	1.29 (1.05–1.57)
Chronic cardiac disease	NS	1.27 (1.09–1.49)
Obesity	NS	1.48 (1.19–1.84)
Valve status*
Native valve	NS	NS
Prosthetic valve	NS	NS
Microbiology**
Staphylococcus aureus	0.65 (0.50–0.85)	0.63 (0.52–0.75)
CNS	NS	1.33 (1.06–1.67)
Streptococci/Enterococci	0.70 (0.54–0.90)	1.38 (1.18–1.61)
Escherichia coli	NS	0.70 (0.50–0.99)
Haemophilus spp	NS	2.87 (1.18–7.01)
Complications
Ischemic stroke	NS	1.30 (1.03–1.65)
Haemorragic stroke	0.36 (0.16–0.82)	0.67 (0.44–1.00)

CNS: coagulase-negative staphylococci.