Table 6. Mixed effects regression¹ of opioid outcomes on between-person and within-person patient logged degree centrality and controls (n = 526,929; n obs = 2,107,716).

	1: Num Rx		2: MME>90		3: Overdose		4: OUD
	IRR	(CI)	OR	(CI)	OR	(CI)	OR	(CI)
Female	1.02***	(1.02–1.03)	0.56***	(0.55–0.58)	1.00	(0.92–1.09)	0.69***	(0.65–0.74)
Age(10 years)	1.05***	(1.05–1.05)	0.91***	(0.90–0.92)	1.01	(0.97–1.04)	0.70***	(0.68–0.72)
Insurance type2
POS	0.85***	(0.84–0.85)	0.47***	(0.45–0.50)	0.54***	(0.48–0.61)	0.53***	(0.49–0.59)
HMO	0.92***	(0.91–0.93)	0.64***	(0.6–0.67)	0.86*	(0.77–0.97)	1.47***	(1.33–1.61)
State3
Kentucky	0.82***	(0.80–0.85)	0.77	(0.60–1.01)	1.39	(0.63–3.04)	0.62*	(0.39–0.98)
Virginia	0.72***	(0.70–0.74)	0.48***	(0.38–0.62)	1.05	(0.49–2.25)	0.23***	(0.15–0.36)
Tennessee	0.73***	(0.71–0.76)	0.61***	(0.47–0.78)	1.06	(0.50–2.27)	1.57*	(1.02–2.43)
Ohio	0.71***	(0.68–0.73)	0.37***	(0.29–0.47)	1.49	(0.70–3.16)	0.23***	(0.15–0.35)
North Carolina	0.67***	(0.65–0.69)	0.58***	(0.45–0.74)	0.96	(0.45–2.04)	0.16***	(0.10–0.24)
Georgia	0.54***	(0.52–0.55)	0.12***	(0.09–0.15)	0.81	(0.38–1.72)	0.17***	(0.11–0.27)
Cancer diagnosis	1.03***	(1.03–1.04)	1.64***	(1.59–1.69)	2.51***	(2.31–2.74)	1.10**	(1.03–1.17)
# opioid prescribers	2.26***	(2.26–2.27)	7.62***	(7.49–7.75)	2.04***	(1.97–2.11)	1.88***	(1.83–1.92)
Network prominence
BP degree logged	1.41***	(1.41–1.42)	3.58***	(3.52–3.64)	1.40***	(1.35–1.45)	3.68***	(3.57–3.79)
WP degree logged	1.40***	(1.39–1.40)	1.93***	(1.90–1.96)	1.22***	(1.17–1.28)	1.33***	(1.30–1.37)
ICC	0.65		0.83		0.57		0.82
BIC	4,581,141		652,846		44,502		181,025

¹Random intercept models adjusted for state fixed effects; incidence rate ratios or odds ratios and confidence intervals are presented

²Omitted category = Other

³Omitted category = West Virginia

* p<0.05

** p<0.01

*** p<0.001