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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Infect Dis Clin North Am. 2019 Jun;33(2):593–609. doi: 10.1016/j.idc.2019.02.007

Table 4:

Safety of live vaccines in household contacts of patients with high-risk immunocompromising conditions86

Vaccine Transmission in high risk household contacts Recommendation Special precautions / Comments
MMR -- Safe
Varicella Mild/subclinical disease Safe If skin lesions develop,

  1. Cover with dressing until scabbed

  2. Avoid direct contact
LAIV -- Do not administer For patients requiring protective isolation, contacts should receive inactivated vaccine
Rotavirus Persistent shedding Safe Avoid handling diapers for 4 weeks
Oral Polio (outside US) Do not administer Use inactivated polio vaccine
Oral Typhoid Safe
Yellow fever Safe

MMR; measles, mumps and rubella

LAIV; live attenuated influenza vaccine