Table 2.
Standard scores of neuropsychological tests conducted at weeks 0, 48 and 96, and percent of youth with impairment
| Week 0 | Week 48 | Week 96 | ||||||
|---|---|---|---|---|---|---|---|---|
| Mean (SD) | n/N (%) with impairment* | Mean (SD) | n/N (%) with impairment* | Mean (SD) | n/N (%) with impairment* | |||
| CCTT1 or CCT1 | ||||||||
| PHIV | 78. 3(17.7) | 30/208 (14.4) | 84.9 (19.1) | 19/188 (10.1) | 89.5 (19.7) | 10/141 (7.1) | ||
| HEU | 83.3 (18.0) | 6/126 (4.8) | 86.9 (18.6) | 11/101 (10.9) | 88 (21.4) | 6/57 (10.5) | ||
| HUU | 84.4 (16.1) | 2/142 (1.4) | 90.4 (16.8) | 4/124 (3.2) | 91.5 (16.9) | 2/84 (2.4) | ||
| CCTT2 or CCT2 | ||||||||
| PHIV | 84.4 (16.9) | 33/208 (15.9) | 88.7 (17.8) | 27/188 (14.4) | 93.2 (19.1) | 20/141 (14.2) | ||
| HEU | 86.4 (16.7) | 14/126 (11.1) | 92.8 (14.2) | 6/101 (5.9) | 94.3 (16.7) | 5/57 (8.8) | ||
| HUU | 91.2 (14.6) | 9/142 (6.3) | 93.5 (14.6) | 6/126 (4.8) | 97.6 (14.0) | 0/84 (0) | ||
| DKEFS Design Fluency | ||||||||
| PHIV | 8.4 (2.6) | 44/231 (19.1) | 9.3 (2.9) | 32/218 (14.7) | 9.6 (2.9) | 19/169 (11.2) | ||
| HEU | 9.7 (2.6) | 10/132 (7.5) | 10.6 (2.7) | 6/111 (5.4) | 10.8 (2.5) | 2/63 (3.2) | ||
| HUU | 10.4 (2.9) | 5/147 (3.4) | 11.3 (2.8) | 2/133 (1.5) | 11.9 (2.7) | 0/96 (0) | ||
| DKEFS Verbal Fluency | ||||||||
| PHIV | 10.1 (3.7) | 42/231 (18.2) | 9.6 (1.8) | 15 (6.9) | 10.7 (3.4) | 19/168 (11.3) | ||
| HEU | 12.2 (3.1) | 6/133 (4.5) | 10.7 (1.6) | 0 (0) | 12.3 (3.1) | 4/62 (6.5) | ||
| HUU | 12.3 (3.3) | 6/147 (4.1) | 11.1 (1.6) | 0 (0) | 12.0 (3.0) | 2/96 (2.1) | ||
*
Impairment defined as ≥2 SD below the age/sex adjusted mean of the HUU group
PHIV = perinatally HIV infected youth; HEU = HIV exposed, uninfected youth and HUU = HIV unexposed, uninfected youth.
CCTT = Children’s Color Trail Test for youth <17 years; CTT = Color Trails Test (ages >18 years); DKEFS = Delis-Kaplan Executive Function System.