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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Environ Toxicol Pharmacol. 2019 Sep 12;72:103263. doi: 10.1016/j.etap.2019.103263

Table 6:

Effects of DDT exposure on the synthesis of IL-6 in PBMCS when the p44/42 or p38 signaling pathways are inhibited.

Fold ↑ synthesis IL-6
[DDT] µM 0.1 0.05 0.025 0.1+I 0.05+I 0.025+I
Inhibitor (I) donor
PD98059 F591 1.6 1.9 1.2 NI NI NI
F592 1.6 1.7 1.9 1.5 1.1 NI
F593 1.4 1.3 2.0 1.8 1.7 3.1
               
SB202190 F591 2.2 2.4 2.2 NI NI NI
F592 1.1 NI 1.4 NI NI 1.5
F595 1.5 2.0 1.8 1.8 2.4 2.4

NI indicates no significant increase ( Fold increase ≤1)