Table 2.
Cumulative incidence (%) of listing, waitlist mortality, and kidney transplantation (KT). Cox proportional hazards were adjusted for age, sex, race and Charlson comorbidity index (CCI) for chance of KT listing. Competing risk models were used to quantify the risk of waitlist mortality by SPPB impairment status (≤ 10) in KT waitlist candidates. Transplant was treated as a competing risk, and models were adjusted for age, sex, race, BMI, cause of end-stage renal disease, blood type, and CCI. Poisson regression was used to calculate the incidence rate ratio of KT and adjusted for age, sex, race, BMI, cause of end-stage renal disease, blood type, and CCI.
| Outcome by SPPB impairment | Cumulative incidence (%) | ||||||
|---|---|---|---|---|---|---|---|
| n | 6 month | 1 year | 3 year | 5 year | |||
| Chance of listing | Adjusted HR | p value | |||||
| No SPPB impairment | 1,495 | 57.4 | 65.7 | 71.2 | 72.6 | REF | |
| SPPB impairment | 1,760 | 45.8 | 54.2 | 58.5 | 59.4 | 0.640.700.77 | <0.001 |
| Risk of waitlist mortality | Adjusted SHR | p value | |||||
| No SPPB impairment | 1,009 | 0.7 | 1.2 | 10.3 | 30.2 | REF | |
| SPPB impairment | 942 | 1.5 | 3.7 | 20.9 | 42.4 | 1.181.562.06 | 0.002 |
| Chance of KT | Adjusted IRR | p value | |||||
| No SPPB impairment | 1,009 | 14.9 | 27.1 | 58.2 | 72.5 | REF | |
| SPPB impairment | 942 | 12.5 | 20.9 | 41.4 | 54.7 | 0.730.840.98 | 0.02 |
HR= hazard ratio, SHR= subhazard ratio, IRR= incidence rate ratio