Table 2:

Area Under the Curve (C-Statistic) of the Modified RxRisk-V Index (RxRisk-VM) in Comparison to and in Combination with Commonly Used Diagnostic Claims-Based Indices

	1-year mortality (95% CI)*	3-year mortality (95% CI)*
Individual Models
Baseline Demographics (Demo)†	0.716 (0.713, 0.719)	0.729 (0.723, 0.731)
Demo + Unique Prescription Count	0.744 (0.740, 0.747)	0.753 (0.751, 0.755)
Demo + RxRisk-V (original weights)	0.759 (0.756, 0.762)	0.767 (0.765, 0.769)
Demo + RxRisk-VM (fully modified version)	0.773 (0.770, 0.776)	0.779 (0.778, 0.781)
Demo + Charlson	0.794 (0.791, 0.797)	0.792 (0.790, 0.794)
Demo + Elixhauser‡	0.800 (0.798, 0.803)	0.796 (0.793, 0.797)
Demo + Gagne	0.810 (0.807, 0.813)	0.805 (0.803, 0.807)
Combined Models
Demo + Charlson + RxRisk-VM	0.805 (0.802, 0.808)	0.803 (0.801, 0.805)
Demo + Elixhauser + RxRisk-VM	0.812 (0.809, 0.815)	0.809 (0.807, 0.811)
Demo + Gagne + RxRisk-VM	0.817 (0.814, 0.819)	0.813 (0.811, 0.815)

^*Models for 1-year and 3-year mortality were compared separately. All comparisons were statistically significant when applying the Chi Square Test of the AUC (p<0.001)

^†Baseline demographic models (demo) includes categorical age (10 categories: <50, 5-year categories between 50-89, and 90+), gender, race/ethnicity, Medicaid enrollment and disability status (original reason for Medicare enrollment).

^‡Elixhauser Index excludes alcohol and drug use due to the redaction of related-claims.