. Author manuscript; available in PMC: 2020 Nov 1.

Published in final edited form as: J Trauma Acute Care Surg. 2019 Nov;87(5):1052–1060. doi: 10.1097/TA.0000000000002398

Table 1. Aggregation of platelets after ADP or PAF stimulation by sex.

Data presented as median (25–75 interquartile range). P value comparing male and female aggregation using Mann-Whitney* or Kruskal-Wallis† tests as appropriate.

Stimulant	ESC (%)
Stimulant	ADP	p value	PAF	p value
By Sex
Females (n=23)	35.5 (31.7−39.2)	0.03*	37.0 (31.0−40.0)	0.49*
Males (n=28)	32.4 (27.5−36.6)	0.03*	34.0 (29.9−40.2)	0.49*
By Sex and Age
Premenopausal females (n=11)	35.2 (31.7−38.2)	0.18†	33.2 (28.2−37.0)	0.05†
Postmenopausal females (n=12)	36.0 (34.4−39.3)		39.6 (37.0−41.3)
Young males (n=15)	32.8 (28.5−36.7)		31.2 (30.3−40.2)
Older males (n=13)	29.3 (24.7−37.2)		37.2 (25.1−40.0)

ADP=adenosine diphosphate, PAF=platelet activating factor, ESC=extent shape change