Table 3.
Correlation of the malignancy of thymoma with survival days, cause of death and sacrifice type in Fischer 344/N rats
| Benign | Malignant |
||
|---|---|---|---|
| without metastasis | with metastasis | ||
| Number of animals | 228 a, b | 28 | 14 |
| Mean survival days c | 713 ± 4 | 609 ± 27 | 506 ± 42 |
| Cause of death: thymoma | 4 | 11 | 11 |
| Sacrifice type | |||
| Natural death | 16 | 8 | 8 |
| Moribund sacrifice | 48 | 9 | 6 |
| Terminal sacrifice | 164 | 11 | 0 |
Seven animals were not included in this table (2 accidental deaths and 5 animals that were sacrificed for interim necropsy).
227 animals were used for calculating mean survival days (1 rat from a study that was terminated early due to high mortality was not included), but 228 animals were used to calculate the number of animals in each sacrifice type.
Study days on which animals were sacrificed. Value shown is group mean ± S.E.