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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Mol Cell Endocrinol. 2019 Aug 20;498:110559. doi: 10.1016/j.mce.2019.110559

Figure 1:

Figure 1:

Development and reproductive characterization of a new global Kiss1r KO mouse made using Cre/lox technology. A) Map of the Kiss1r allele in the original gene-trap Kiss1r KO mouse line and the Kiss1r flox line used in this study. B) Schematic of the simplified strategy for creating the new global Kiss1r KO (“gKO”) by crossing Zp3-Cre and Kiss1r flox strains. C) Image of testes of adult gKO and WT males. D) Ovary and testes weights of adult gKO and control mice (n=6–9/genotype for each sex). E) AGD of adult male gKOs (n=10–15/genotype). **, p<0.01, ***p<0.001.