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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Mol Cell Endocrinol. 2019 Sep 5;498:110574. doi: 10.1016/j.mce.2019.110574

Fig. 3. Neuronal projections of the arcuate nucleus are not affected by POMC-specific GHR disruption.

Fig. 3.

A. Representative photomicrograph showing POMC-immunoreactivity (POMC-ir) in ARH neurons of control mice. B-D. Representative photomicrographs showing POMC innervation in different hypothalamic areas of control mice. E. Representative photomicrograph showing POMC neurons in the ARH of POMC GHR KO mice. F-H. Representative photomicrographs showing POMC innervation in different hypothalamic areas of POMC GHR KO mice. I-N. Representative photomicrographs showing AgRP innervation in different hypothalamic areas of control (I-K) and POMC GHR KO mice (L-N). Abbreviations: 3V, third ventricle; ARH, arcuate nucleus of the hypothalamus; DMH, dorsomedial nucleus of the hypothalamus; LHA, lateral hypothalamic area; PVH, paraventricular nucleus of the hypothalamus. Scale bars: A = 100 μm; B = 200 μm.