Table 2.
No. | Cyclodextrin | Substituent | Inhibition of a single αHL channel in model lipid membranes, IC50 (nM) | Inhibition of αHL toxicity, IC50 (μM) |
---|---|---|---|---|
1 | α | >5000 | >100 | |
2 | β | *50 | 3.3 ± 2.3 | |
3 | γ | >5000 | >100 |
No. | Cyclodextrin | Substituent | Inhibition of a single αHL channel in model lipid membranes, IC50 (nM) | Inhibition of αHL toxicity, IC50 (μM) |
---|---|---|---|---|
1 | α | >5000 | >100 | |
2 | β | *50 | 3.3 ± 2.3 | |
3 | γ | >5000 | >100 |