Table 5.
Mixed model for coagulatory markers, fibrinogen, vWF, factor VIII, by exposure class and antilog values
| Exposure | Fibrinogen | vWF | Factor VIII | ||||||
|---|---|---|---|---|---|---|---|---|---|
| β | 95% CI | β | 95% CI | β | 95% CI | ||||
| Respirable quartz (mg/m3 p) | |||||||||
| > 0.05 | 1.04 | 0.90 | 1.21 | 1.06 | 0.81 | 1.40 | 1.06 | 0.85 | 1.33 |
| 0.01–0.05 | 1.06 | 0.97 | 1.15 | 1.00 | 0.86 | 1.18 | 1.04 | 0.91 | 1.18 |
| < 0.01 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Respirable dust (mg/m3 p) | |||||||||
| > 1.0 | 1.10 | 0.96 | 1.26 | 0.98 | 0.77 | 1.26 | 1.11 | 0.89 | 1.39 |
| 0.1–1.0 | 1.03 | 0.94 | 1.12 | 0.94 | 0.82 | 1.07 | 1.05 | 0.91 | 1.22 |
| < 0.1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Inhalable dust (mg/m3 s) | |||||||||
| > 5 | 1.14 | 0.94 | 1.39 | 0.90 | 0.63 | 1.29 | 1.36 | 1.03 | 1.81 |
| 0.1–5 | 1.07 | 0.91 | 1.26 | 0.92 | 0.69 | 1.23 | 1.27 | 1.01 | 1.59 |
| < 0.1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Total dust (mg/m3 s) | |||||||||
| > 5 | 1.08 | 0.93 | 1.25 | 0.98 | 0.76 | 1.28 | 1.13 | 0.92 | 1.40 |
| 0.1–5 | 1.02 | 0.93 | 1.12 | 1.05 | 0.89 | 1.24 | 1.06 | 0.93 | 1.21 |
| < 0.1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Respirable dust (mg/m3 s) | |||||||||
| > 1.0 | 1.05 | 0.91 | 1.22 | 0.84 | 0.64 | 1.09 | 1.17 | 0.94 | 1.45 |
| 0.1–1.0 | 0.98 | 0.86 | 1.11 | 0.80 | 0.64 | 1.00 | 1.04 | 0.87 | 1.24 |
| < 0.1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Respirable quartz (mg/m3 s) | |||||||||
| > 0.05 | 1.04 | 0.90 | 1.20 | 1.04 | 0.80 | 1.35 | 1.13 | 0.92 | 1.40 |
| 0.01–0.05 | 1.09 | 0.99 | 1.20 | 1.08 | 0.91 | 1.29 | 1.10 | 0.96 | 1.27 |
| < 0.01 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| PM 10 (mg/m3 s) | |||||||||
| > 2.5 | 1.13 | 0.92 | 1.40 | 0.85 | 0.59 | 1.24 | 1.39 | 1.03 | 1.87 |
| 0.1–2.5 | 1.06 | 0.87 | 1.28 | 0.77 | 0.55 | 1.09 | 1.18 | 0.90 | 1.54 |
| < 0.1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| PM 2.5 (mg/m3 s) | |||||||||
| > 2 | 1.15 | 0.97 | 1.37 | 0.90 | 0.66 | 1.23 | 1.26 | 0.98 | 1.62 |
| 0.1–2 | 1.09 | 0.96 | 1.24 | 0.92 | 0.73 | 1.15 | 1.18 | 0.98 | 1.41 |
| < 0.1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| PM 1 (mg/m3 s) | |||||||||
| > 0.5 | 1.04 | 0.89 | 1.22 | 0.87 | 0.66 | 1.15 | 1.08 | 0.86 | 1.35 |
| 0.1–0.5 | 1.03 | 0.94 | 1.13 | 1.07 | 0.90 | 1.26 | 1.11 | 0.97 | 1.28 |
| < 0.1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Particle surface area (µm2/cm3 s) | |||||||||
| > 10 | 1.06 | 0.92 | 1.23 | 0.93 | 0.72 | 1.21 | 1.06 | 0.86 | 1.30 |
| 2–10 | 1.09 | 1.00 | 1.20 | 1.01 | 0.85 | 1.19 | 1.10 | 0.96 | 1.26 |
| < 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Particle number (nr/104 cm3 s) | |||||||||
| > 1000 | 1.11 | 1.00 | 1.24 | 1.07 | 0.88 | 1.31 | 1.11 | 0.95 | 1.31 |
| 100–1000 | 1.07 | 0.97 | 1.18 | 0.96 | 0.80 | 1.15 | 1.08 | 0.93 | 1.25 |
| < 100 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
β fixed effect by exposure class, 95% CI (confidence interval)
Bold values indicate exposure response, both significant and nonsignificant, and italic significant in the high exposure class
p personal sampling, s stationary sampling