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. 2019 Aug 21;471(10):1305–1316. doi: 10.1007/s00424-019-02304-0

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© The Author(s) 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — Representative force recordings for soleus and extensor digitorum longus muscles during maximal stimulation frequencies. Forces are shown for a given muscle before (solid line) and after (dashed line) treatment. Soleus muscles were stimulated at 100 Hz before and after exposure to diluent (a) or ISO (b). Extensor digitorum longus (EDL) muscles were stimulated at 150 Hz before and after exposure to diluent (c) or ISO (d). Note that at these frequencies ISO enhanced force markedly more in soleus than in EDL