Table 1.
An overview of proteins, phosphoproteins and phosphosites quantified in this study.
| Biological replicate 1 | Biological replicate 2 | Biological replicate 3 | Total | |
|---|---|---|---|---|
| Total protein | ||||
| Unregulated | 1775 | 1845 | 1771 | 1942 |
| Significantly upregulated | 83 | 68 | 98 | 201 |
| Significantly downregulated | 57 | 72 | 60 | 120 |
| Phosphoproteins | ||||
| Unregulated | 549 | 622 | 617 | 611 |
| Significantly upregulated | 53 | 49 | 41 | 103 |
| Significantly downregulated | 28 | 38 | 55 | 85 |
| Phosphosites | ||||
| Unregulated | 1563 | 1840 | 1947 | 1939 |
| Significantly upregulated | 178 | 124 | 70 | 301 |
| Significantly downregulated | 107 | 79 | 64 | 200 |
In total, 2263 proteins, 799 phosphoproteins and 2440 phosphosites were quantified. Gaussian distribution (mean ± 1.96SD) was applied to filter out the significantly regulated proteins/sites.