Fig. 2. DDX17 is upregulated in HCC tissues and was associated with poor prognosis in HCC patients.

a, b Expression of DDX17 increased as HCC progressed to more advanced stages. DDX17 protein expression was accessed by IHC analysis in 105 paired HCC specimens. The IHC score of DDX17 was calculated as the staining intensity (0, 1, 2, or 3) × the staining extent (0–100%). c DFS curve of HCC patients based on DDX17 expression according to Kaplan–Meier analysis. d OS curve of HCC patients based on DDX17 expression according to Kaplan–Meier analysis. Patients with high levels of DDX17 were prominently associated with poor DFS (p = 0.001) and OS (p < 0.001). e, f OS curve of HCC patients with different DDX17 expression was further analyzed according to tumor stage. *p < 0.05