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. 2019 Oct 21;7:65–79. doi: 10.2147/HP.S217955

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© 2019 Spears.

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Transmission electron microscopy (TEM) of porcine myocardium at 3 hrs of reperfusion following 1 hr of coronary occlusion. Representative images from control (left panel) and SSO₂-treated (right panel) groups (masked assignment selection by cardiac pathologist [Vander Heide R]) (data from Spears et al,¹¹⁷). EC = Endothelial Cell. RBC = Red Blood Cell (within lumen of EC). EC edema, loss of EC nuclei, and prominent disruption of myofibrillar structure was evident in the Control group only. Reprinted by permission from Springer Nature (Springer Nature) (Am J Cardiovasc Drugs) (Hyperoxemic perfusion for treatment of reperfusion microvascular ischemia in patients with myocardial infarction) Bartorelli AL., Copyright (2003).¹²⁰