Table 3.
AUCs obtained using sex and age alone, SNPs alone, and all three together.
Condition | Test set | Age + Sex | Genetic Only | Age + Sex + genetic |
---|---|---|---|---|
Hypertension | UKBB | 0.638 (0.018) | 0.667 (0.012) | 0.717 (0.007) |
Hypothyroidism | UKBB | 0.695 (0.007) | 0.705 (0.009) | 0.783 (0.008) |
Type 2 Diabetes | UKBB | 0.672 (0.009) | 0.640 (0.015) | 0.651 (0.013) |
Hypertension | eMERGE | 0.818 (0.008) | 0.651 (0.007) | 0.851 (0.009) |
Resistant Hypertension | eMERGE | 0.817 (0.008) | 0.686 (0.007) | 0.864 (0.009) |
Hypothyroidism | eMERGE | 0.643 (0.006) | 0.630 (0.006) | 0.697 (0.007) |
Type 2 Diabetes | eMERGE | 0.565 (0.006) | 0.633 (0.006) | 0.651 (0.007) |