Table 3.
Ratios of specific sterol to cholesterol concentrations in umbilical cord vein of IUGR and CTRL neonates
| CTRL (n = 49) | IUGR (n = 49) | p-value | ||||
|---|---|---|---|---|---|---|
| Sterol to TC ratio | μmol/mmol *10exp3 | Median | 95% CI | Median | 95% CI | |
| Lathosterol/TC | Ratio | 2.183 | (2.049–2.523) | 2.081 | (1.894–2.276) | 0.2952 |
| Dihydro-lanosterol/TC | Ratio | 0.006 | (0.005–0.008) | 0.006 | (0.005–0.008) | 0.6267 |
| Desmosterol/TC | Ratio | 1.156 | (1.080–1.259) | 1.522 | (1.399–1.586) | < 0.0001 |
| Lanosterol/TC | Ratio | 0.187 | (0.167–0.206) | 0.175 | (0.145–0.206) | 0.1795 |
| 24OH cholesterol/TC | Ratio | 0.075 | (0.065–0.084) | 0.108 | (0.091–0.123) | < 0.0001 |
| 27OH cholesterol/TC | Ratio | 0.033 | (0.030–0.035) | 0.047 | (0.043–0.050) | < 0.0001 |
| β-sitosterol/TC | Ratio | 0.420 | (0.354–0.481) | 0.478 | (0.418–0.558) | 0.0210 |
| Campesterol/TC | Ratio | 0.387 | (0.360–0.429) | 0.469 | (0.437–0.569) | 0.0002 |
| 5α-cholestanol/TC | Ratio | 5.990 | (5.426–6.489) | 6.924 | (6.515–7.175) | 0.0004 |
| Stigmasterol/TC | Ratio | 0.075 | (0.069–0.085) | 0.082 | (0.070–0.094) | 0.1585 |
| Brassicasterol/TC | Ratio | 0.045 | (0.040–0.053) | 0.059 | (0.055–0.066) | 0.0001 |
Significant p-values are in bold