Fig. 4.

Neocentromeres occupy the pericentromeric repetitive sequences asymmetrically. Cnp1 ChIP-seq reads mapped to centromeric and pericentromeric regions of all 3 chromosomes in cen2^inactive (dark pink), cen1^inactive (dark blue), and cen1^active with Cnp1 spreading (magenta). ura4 cassette was inserted into the right side of the otr1R (otr1R::ura4) and labeled by a red asterisk. Chromosomes 1 and 2 and ura4 cassette are shown. #1 and #2, Biological replicate 1 and 2. Diagrams, x axis and y axis, same as in Fig. 1.