Table 2.
Time from brain death to cross clamp | ||||
---|---|---|---|---|
Variable | < 24 hours | 24–60 hours | > 60 hours | p-value |
(n=2,455) | (n=15,097) | (n=2,169) | ||
Donor male gender | 60.0% (1, 472) | 59.9% (9, 043) | 61.7% (1, 339) | 0.261 |
Donor age (median, IQR) | 35 (26.5) | 32 (24) | 32 (23) | < 0.001 |
Donor BMI (median, IQR) | 24.9 (6.1) | 25.2 (6.4) | 25.7 (6.6) | < 0.001 |
Donor ethnicity | < 0.001 | |||
White | 73.0% (1, 792) | 62.3% (9, 403) | 42.9% (931) | |
Black | 15.2% (372) | 19.8% (2, 991) | 20.6% (446) | |
Hispanic | 8.6% (210) | 13.9% (2, 100) | 29.3% (636) | |
Other | 3.3% (81) | 4.0% (603) | 7.2% (156) | |
Donor history | ||||
Cigarette use | 11.6% (286) | 9.2% (1, 396) | 6.1% (132) | < 0.001 |
Cocaine use | 10.3% (254) | 13.5% (2, 041) | 14.8% (321) | < 0.001 |
Alcohol abuse | 12.4% (304) | 13.9% (2, 105) | 14.6% (316) | 0.065 |
Diabetes | 7.5% (185) | 7.0% (1, 058) | 7.1% (153) | 0.639 |
Hypertension | 24.6% (604) | 23.3% (3, 511) | 21.7% (471) | 0.068 |
Cancer | 2.6% (64) | 1.9% (290) | 1.1% (23) | 0.001 |
Pulmonary infection | 40.7% (998) | 56.4% (8, 522) | 72.5% (1, 573) | < 0.001 |
Donor creatinine (median, IQR) | 1.0 (0.6) | 1.0 (0.7) | 1.0 (0.9) | < 0.001 |
Donor bilirubin (median, IQR) | 0.8 (0.7) | 0.7 (0.6) | 0.8 (0.7) | < 0.001 |
Donor cause of death | < 0.001 | |||
Anoxia | 14.8% (363) | 18.5% (2, 790) | 23.7% (515) | |
Cerebrovascular/stroke | 40.1% (984) | 33.0% (4, 985) | 29.2% (634) | |
Head trauma | 42.6% (1, 046) | 45.4% (6, 848) | 44.1% (957) | |
CNS tumor | 0.5% (12) | 0.7% (100) | 0.7% (15) | |
Other | 2.0% (50) | 2.5% (374) | 2.2% (48) | |
Organs recovered for transplant (median, IQR) | 6 (2) | 6 (2) | 6 (1) | < 0.001 |
ABO blood type | 0.004 | |||
A | 37.4% (917) | 36.6% (5, 529) | 33.4% (724) | |
B | 11.1% (273) | 10.8% (1, 630) | 10.6% (230) | |
AB | 2.4% (60) | 2.2% (337) | 1.6% (34) | |
O | 49.1% (1, 205) | 50.3% (7, 601) | 54.4% (1, 181) | |
Graft ischemic time (hours, median, IQR) | 5.0 (2.1) | 5.0 (2.1) | 4.9 (2.2) | < 0.001 |
IQR, interquartile range; BMI, body mass index; CNS, central nervous system