Table 3.

Diagnostic criteria of tested parameters and CA 15–3 in patients with breast cancer

Tested parameters	Diagnostic criteria (%)	Breast cancer
		I stage	II stage	III stage	IV stage	Total group
CA 15–3	SE SP PPV NPV	39.47 95.00 83.33 71.25	46.34 95.00 86.36 72.15	75.00 95.00 83.33 91.94	90.48 95.00 86.36 96.61	58.33 95.00 95.89 53.27
VEGF-A	SE SP PPV NPV	55.26 76.67 60.00 73.02	70.73 76.67 67.44 79.31	70.00 76.67 50.00 88.46	66.67 76.67 50.00 86.79	65.00 76.67 84.78 52.27
VEGF-C	SE SP PPV NPV	68.42 75.00 63.41 78.95	68.29 75.00 65.12 77.59	60.00 75.00 44.44 84.91	61.90 75.00 46.43 84.91	65.83 75.00 84.04 52.33
VEGF-D	SE SP PPV NPV	71.05 35.00 40.91 65.63	90.24 35.00 48.68 84.00	100.00 35.00 33.90 100.00	71.43 35.00 27.78 77.78	82.50 35.00 71.74 50.00
VEGFR-2	SE SP PPV NPV	52.63 53.33 41.67 64.00	65.85 53.33 49.09 69.57	65.00 53.33 31.71 82.05	71.43 53.33 34.88 84.21	62.50 53.33 72.82 41.56
CA 15–3 + VEGF-A	SE SP PPV NPV	71.05 73.33 62.79 80.00	78.05 73.33 66.67 83.02	100.00 73.33 55.55 100.00	100.00 73.33 56.68 100.00	83.33 73.33 86.21 68.75
CA 15–3 + VEGF-C	SE SP PPV NPV	78.95 70.00 62.50 84.00	82.93 70.00 65.38 85.71	95.00 70.00 51.35 97.67	100.00 70.00 53.85 100.00	86.67 70.00 85.25 72.41
CA 15–3 + VEGF-D	SE SP PPV NPV	81.58 35.00 44.29 75.00	92.68 35.00 49.35 87.50	100.00 35.00 33.90 100.00	100.00 35.00 35.00 100.00	91.67 35.00 73.83 67.74
CA 15–3 + VEGFR-2	SE SP PPV NPV	71.05 51.67 48.21 73.81	78.05 51.67 52.46 77.50	80.00 51.67 35.55 88.57	100.00 51.67 42.00 100.00	80.00 51.67 76.80 56.36