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. 2019 Oct 26;19:1006. doi: 10.1186/s12885-019-6140-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Progression-free survival (a) and overall survival (b) in patients with brain metastases treated with gefitinib, erlotinib, or afatinib; overall survival in patients with different numbers of brain metastases (c), different epidermal growth factor receptor gene mutation types (d), concomitant liver metastases (e), and different M stages (f); overall survival in patients with and without radiotherapy (g) and with and without surgical excision (h); and overall survival in patients with different locations of disease progression (i)