Table 3.
Risk factors for death in HIV infected children
| Variable | Total (N=159) | Died, n (%) (n=84) | Survived, n (%) (n=75) | Crude OR [95% CI] | Adjusted OR [95% CI] |
|---|---|---|---|---|---|
| Age ≤5 years | |||||
| Yes | 36 | 27 (75.00) | 9 (25.00) | 3.47 [1.51-7.99] | 6.50 [1.96-21.50] |
| No | 123 | 57 (46.34) | 66 (53.66) | 1.00 | 1.00 |
| Sex | |||||
| Male | 81 | 43 (53.09) | 38 (46.91) | 1.02 [0.54-1.90] | 0.98 [0.41-2.31] |
| Female | 78 | 41 (52.56) | 37 (47.44) | 1.00 | 1.00 |
| Re-treatment | |||||
| Yes | 34 | 22 (64.71) | 12 (35.29) | 1.86 [0.85-4.08] | 1.27 [0.37-4.39] |
| No | 125 | 62 (49.60) | 63 (50.40) | 1.00 | 1.00 |
| History of TB contact | |||||
| Yes | 116 | 62 (53.45) | 54 (46.55) | 1.09 [0.54-2.20] | 1.32 [0.49-3.54] |
| No | 43 | 22 (51.16) | 21 (48.84) | 1.00 | 1.00 |
| BGC vaccine scar | |||||
| No | 20 | 12 (60.00) | 8 (40.00) | 1.39 [0.53-3.62] | 1.84 [0.45-7.42] |
| Yes | 139 | 72 (51.80) | 67 (48.20) | 1.00 | 1.00 |
| Anorexia | |||||
| Yes | 113 | 62 (54.87) | 51 (45.13) | 1.32 [0.66-2.63] | 1.04 [0.38-2.82] |
| No | 46 | 22 (47.83) | 24 (52.17) | 1.00 | 1.00 |
| Night sweats | |||||
| Yes | 62 | 28 (45.16) | 34 (54.84) | 0.60 [0.32-1.14] | 0.88 [0.34-2.28] |
| No | 97 | 56 (57.73) | 41 (42.27) | 1.00 | 1.00 |
| Weight loss | |||||
| Yes | 112 | 61 (54.46) | 51 (45.54) | 1.25 [0.63-2.47] | 1.42 [0.51-3.92] |
| No | 47 | 23 (48.94) | 24 (51.06) | 1.00 | 1.00 |
| Poor nutritional status (WAZ ≤ -2 SD) | |||||
| Yes | 73 | 60 (82.19) | 13 (17.81) | 11.92 [5.56-25.56] | 23.55 [8.20-67.64] |
| No | 86 | 24 (27.91) | 62 (72.09) | 1.00 | 1.00 |
| Fever >2 weeks | |||||
| Yes | 130 | 67 (51.54) | 63 (48.46) | 0.75 [0.33-1.69] | 0.69 [0.23-2.06] |
| No | 29 | 17 (58.62) | 12 (41.38) | 1.00 | 1.00 |
| Cough >2 weeks | |||||
| Yes | 87 | 38 (43.68) | 49 (56.32) | 1.00 | 1.00 |
| No | 72 | 46 (63.89) | 26 (36.11) | 2.28 [1.20-4.33] | 0.53 [0.19-1.47] |
| Lymphadenopathy | |||||
| Yes | 71 | 39 (54.93) | 32 (45.07) | 1.16 [0.62-2.18] | 1.37 [0.54-3.45] |
| No | 88 | 45 (51.14) | 43 (48.86) | 1.00 | 1.00 |
| Type of TB | |||||
| EPTB | 36 | 23 (63.89) | 13 (36.11) | 1.79 [0.83-3.87] | 1.42 [0.35-4.76] |
| PTB | 123 | 61 (49.59) | 62 (50.41) | 1.00 | 1.00 |
| TST | |||||
| Negative | 68 | 38 (55.88) | 30 (44.12) | 1.24 [0.66-2.32] | 0.39 [0.15-1.01] |
| Positive | 91 | 46 (50.55) | 45 (49.45) | 1.00 | 1.00 |
| AFB testing | |||||
| Positive | 30 | 9 (30.00) | 21 (70.00) | 1.00 | 1.00 |
| Negative | 129 | 75 (58.14) | 54 (41.86) | 3.24 [1.37-7.62] | 4.51 [1.08-18.70] |
HIV: human immunodeficiency virus; SD: standard deviation; TB: tuberculosis; TST: Tuberculin skin test; AFB: Acid Fast Bacilli; WAZ: Weight-for-Age Z-score; EPTB: Extra pulmonary tuberculosis; PTB: Pulmonary tuberculosis; OR: odds ratio; 95% CI: 95% confidence interval